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KMID : 0043320010240050371
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Archives of Pharmacal Research
2001 Volume.24 No. 5 p.371 ~ p.376
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One-pot Synthesis of Cinnamylamines with Various Protecting Groups from Cinnamyl Ethers
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Jung Young-Hoon
Kim Ji-Duck
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Abstract
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The reaction of various alkyl cinnamyl ethers with CSI afforded the corresponding cinnamylamines with various protecting groups, such as -NHMoc, -NHiPoc, -NHCbz, -NHPnz, -NHTroc and -NHAloc. In the case of cinnamyl t-butyl ether and cinnamyl p-methoxybenzyl ether, the corresponding cinnamyl carbamates were formed via a different reaction pathway from the above.
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KEYWORD
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Cinnamylamines, Chlorosulfonyl isocyanate, Alkyl cinnamyl ethers, Carbamates, Protecting group
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